Izindaba

Ukuba nokwenzeka nokuphepha kokuvuselelwa ngemuva kwe-venous thromboembolism

Abstract

Ingemuva

I-venous thromboembolism yisifo esisongela ukuphila. Kwabasindile, amazinga ahlukene ezikhalazo zokusebenza adinga ukubuyiselwa noma avinjwe (isb., i-post-thrombotic syndrome, i-pulmonary hypertension). Ngakho-ke, ukuvuselelwa ngemuva kwe-venous thromboembolism kunconywa eJalimane. Kodwa-ke, uhlelo lokubuyisela esimweni esihlelekile alikachazwanga lesi sibonakaliso. Lapha, sethula ulwazi lwesikhungo esisodwa sokuhlunyeleliswa kwezimilo.

Izindlela

Idatha evela ngokulandelanai-pulmonary embolism(PE) iziguli ezathunyelwa ohlelweni lokuhlunyeleliswa kweziguli ezilaliswe amasonto ama-3 kusukela ngo-2006 kuya ku-2014 zahlolwa ngokuphindaphindiwe.

Imiphumela

Zingu-422 iziguli ezihlonziwe. Iminyaka yobudala emaphakathi yayiyiminyaka engu-63.9±13.5, inkomba yesisindo somzimba (BMI) yayiyi-30.6±6.2 kg/m2, kanti ama-51.9% kwakungabesifazane. I-Deep vein thrombosis ngokusho kwe-PE yaziwa ngama-55.5% azo zonke iziguli. Sisebenzise ukungenelela okubanzi kokwelapha okufana nokuqeqeshwa kwebhayisikili ngezinga lokushaya kwenhliziyo eligadiwe ku-86.7%, ukuqeqeshwa kokuphefumula ngo-82.5%, ukwelapha emanzini/ukubhukuda ngo-40.1%, kanye nokwelashwa kokuqeqeshwa kwezokwelapha ku-14.9% yazo zonke iziguli. Izehlakalo ezimbi (AEs) zenzeke ezigulini ezingu-57 phakathi nenkathi yokuvuselela yamaviki angu-3. Ama-AE avamile ayebanda (n=6), isifo sohudo (n=5), kanye nokutheleleka komgudu wokuphefumula ongaphezulu noma ophansi owalashwa ngama-antibiotics (n=5). Kodwa-ke, iziguli ezintathu ezingaphansi kwe-anticoagulation therapy zahlushwa ukopha, okwakubalulekile ngokomtholampilo kokukodwa. Iziguli ezine (0.9%) kwadingeka ukuba zidluliselwe esibhedlela sokunakekelwa okuyinhloko ngezizathu ezingahlobene ne-PE (i-acute coronary syndrome, ithumba le-pharyngeal, kanye nezinkinga zesisu ezibuhlungu). Alikho ithonya lanoma yikuphi ukungenelela kokusebenza ngokomzimba okwenzekayo kwanoma iyiphi i-AE etholakele.

Isiphetho

Njengoba i-PE iyisifo esisongela ukuphila, kubonakala kunengqondo ukuncoma ukuvuselelwa okungenani ezigulini ze-PE ezinengozi ephakathi noma ephezulu. Kuboniswa okokuqala kulolu cwaningo ukuthi uhlelo lokuvuselela olujwayelekile ngemuva kwe-PE luphephile. Kodwa-ke, ukusebenza kahle nokuphepha esikhathini eside kudinga ukucutshungulwa ngokuzayo.

Amagama angukhiye: i-venous thromboembolism, i-pulmonary embolism, ukuvuselelwa