Ngo-1968, iKruger-theimer ifanekise ukuthi amamodeli we-pharmacokinetetic angasetshenziswa kanjani ukuklama ama-regimens wedosi elifanele. Le BOLUS, Ukuqedwa, Ukudlulisa (ukubheja) regimen kuqukethe:
Umthamo we-bolus ubalwe ukugcwalisa inkatho ephakathi (igazi),
Ukufakwa kwezinga elihlala lilingana nezinga lokuqedwa,
ukumnika okunxephezela ukudluliselwa kwezicubu ezihlanzeke: [okuncipha ngokuncipha kwezinga]
Ukuzilolonga kwendabuko kwakubandakanya ukubala irejimeni yokumiliselwa ye-proPofol yindlela ye-Roberts. Ithamo eli-1.5 mg / kg lilandelwa umthamo we-10 mg / kg / ihora elincishiswe kumanani ka-8 no-6 mg / kg / hr ngezikhathi eziyishumi.
Ukuqondiswa kwesayithi okuqondisiwe
Imiphumela eyinhloko yeisilalisa zinhlunguAma-Intravenous Agents yimiphumela edidithi neye-hypnotic kanye nesayithi lapho umuthi ubhekana nale miphumela, kuthiwa indawo yindawo yobuchopho. Ngeshwa akunakwenzeka ekusebenzeni kwemitholampilo ukukala okuhlushwa ubuchopho [Itho lendawo]. Noma ngabe singakwazi ukukala ukugxila kobuchopho okuqondile, kungadingeka ukwazi ukugxila okuqondile kwesifunda noma ukugxila kwe-receptor lapho umuthi usebenza khona.
Ukuthola Ukuhlushwa Okuguquguqukayo Okuqhubekayo
Umdwebo ongezansi ukhombisa isilinganiso sokumnika esidingekayo esilinganisweni esinciphayo esithe xaxa ngemuva komthamo we-bolus ukuze silondoloze ukugxila kwegazi okuqhubekayo kwe-propofol. Ibonisa futhi i-lag phakathi kwegazi nokuhlushwa kwesiza.
Isikhathi sePosi: Nov-05-2024